WNT-mediated signaling relay in stem cells and oncogenesis - from basic biology to applications

Training Program

WntsApp offers an extensive training program to 15 incoming young researchers (12 early stage researchers (ESR) and 3 experienced researchers (ER)). Central to the quality of the training program are the individual research projects. All projects have an interdisciplinary component and international and industry collaborations. The contributions of the international and private sector associate partners to the training are clearly defined. Interactions within the network are strengthened by meaningful secondments of at least 1 month each.

The training covers:
(1) specialist training in an international, interdisciplinary and intersectorial research project
(2) advanced technology training courses
(3) professional training in transferable skills

Advanced training courses

The core of the specialist training of WntsApp is a multidisiplinary set of 5 advanced courses, organised by academic and private partners:

Module Title Organizer Objective Length
Introductory course Wnt signaling –
From molecule to disease
Introduction latest mechanisms and models in WNT signalling and its relationship to human physiology and disease 3 days;
1 ECTS
Advanced course Biophyhsics of protein-protein interactions Analysis of protein complexes, including quantitative biophysical methods and the use of modulating peptides 3 days;
1 ECTS
Advanced course GPCR/Frizzled receptor pharmacology Provide in-depth knowledge on GPCR receptor pharmacology, including quantitative methods for ligand-receptor interactions 3 days;
1 ECTS
Advanced course Mouse models for human disease Genetic engineering, transgenics, conditional knock-out systems, cell lineage tracing, organoid cultures and ethical issues 3 days;
1 ECTS
Advanced course Screening, validation and optimization therapeutic peptides Peptide design, synthesis, high diversity library screens, cyclic peptides, bioassays for lead drugs 3 days;
1 ECTS

Training of key transferable skills

WntsApp offers ESR/ER training in the key transferable skills for personal and professional development (totalling 3,6 ECTS):

Module Title Organizer Objective Length
Course Entrepreneurship, IP issues and exploitation results Valorisation, patents, licenses, royalties, public-private partnerships, venture capital and entrepreneurship 2 days;
0.6 ECTS
Course Scientific writing Writing articles and grants, academic tone and style, avoiding plagiarism, composing cover letters and CVs 2 days;
0.6 ECTS
Course Learning from the publishers’s perspective
Together with Elsevier (AP4)
How to contact an editor, pitfalls to avoid, ethics, submission process, bibliometrics, visibility, international competition, open access 2 days;
0.6 ECTS
Workshop Research management and personal effectiveness
Together with PCDI (AP3)
Self-management, personal effectiveness, mentor-trainee interaction, negotiation, exerting influence, discover one’s core qualities 2 days;
0.6 ECTS
Workshop Communication and presentation skills
Together with PCDI (AP3)
Presenting and effective communication, outreach and teamwork 2 days;
0.6 ECTS
Workshop People, politics and power
Together with PCDI (AP3)
Awareness of international developments in science and biotech. Developing a vision, defingin career path, intersectorial interactions, personal leadership and networking 2 days;
0.6 ECTS